[1]祖力胡马尔?玉素甫,董晶晶,郭蔚,等.不同民族和地区女性围绝经期高血压中医证型与靶器官损害相关性研究[J].齐鲁医学杂志,2017,32(03):301-304,307.[doi:10.13362/j.qlyx.201703016]
 ZULHUMAR?Yusufu,DONG Jingjing,GUO Wei,et al.ASSOCIATION BETWEEN HYPERTENTION TCM SYNDROME TYPES AND TARGET ORGAN INJURY IN PERIMENOPAUSAL PERIOD OF WOMEN FROM DIFFERENT NATIONALITIES AND REGIONS[J].Medical Journal of Qilu,2017,32(03):301-304,307.[doi:10.13362/j.qlyx.201703016]
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不同民族和地区女性围绝经期高血压中医证型与靶器官损害相关性研究()
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《齐鲁医学杂志》[ISSN:1008-0341/CN:37-1280/R]

卷:
第32卷
期数:
2017年03期
页码:
301-304,307
栏目:
出版日期:
2017-08-07

文章信息/Info

Title:
ASSOCIATION BETWEEN HYPERTENTION TCM SYNDROME TYPES AND TARGET ORGAN INJURY IN PERIMENOPAUSAL PERIOD OF WOMEN FROM DIFFERENT NATIONALITIES AND REGIONS
文章编号:
1008-0341(2017)03-0301-05
作者:
祖力胡马尔?玉素甫1董晶晶1郭蔚2刘永明2
1 乌鲁木齐市中医医院,新疆 乌鲁木齐 830000; 2 上海中医药大学附属曙光医院
Author(s):
ZULHUMAR?Yusufu DONG Jingjing GUO Wei LIU Yongming
Traditional Chinese Medicine Hospital of Urumqi, Urumqi 830000, China
关键词:
高血压围绝经期地区民族医学中国传统危及器官
Keywords:
hypertension perimenopause regions nationalities medicine Chinese traditional organs at risk
分类号:
R544.1;R259
DOI:
10.13362/j.qlyx.201703016
文献标志码:
A
摘要:
目的 观察不同民族、地区女性围绝经期高血压病人中医证型分布规律及其与靶器官损害的相关性。
方法 选取300例不同民族、地区女性围绝经期高血压病人,采集其一般资料、中医症状以及靶器官损害资料。比较维吾尔族(简称维族)和汉族、新疆地区和上海地区汉族女性围绝经期高血压病人中医证型分布、24 h动态血压、颈动脉内中膜厚度(IMT)、颈动脉斑块检出率和室间隔厚度。
结果 维族组围绝经期高血压病人中医证型分布从高到低依次为肝阳上亢、痰湿壅盛、肝肾阴虚和气阴两虚,汉族组病人依次为肝肾阴虚、肝阳上亢、气阴两虚和痰湿壅盛,差异有统计学意义(χ2=12.61,P<0.05)。新疆地区汉族围绝经期高血压病人中医证型分布从高到低依次为肝阳上亢、肝肾阴虚、气阴两虚和痰湿壅盛,上海地区病人中医证型分布从高到低依次为肝肾阴虚、肝阳上亢、气阴两虚和痰湿壅盛,差异无统计学意义(P>0.05)。维族组病人的24 h收缩压和24 h平均动脉压高于汉族组,差异有统计学意义(t=2.85、3.46,P<0.05);新疆地区汉族组病人24 h收缩压、24 h舒张压、24 h平均动脉压较上海地区汉族组病人高,但差异无统计学意义(P>0.05);各组均以肝阳上亢证病人血压最高。维族组病人颈动脉IMT、颈动脉斑块检出率均高于汉族组病人,差异有统计学意义(t=4.76,χ2=7.35,P<0.05);新疆地区汉族组病人颈动脉IMT、颈动脉斑块检出率均高于上海地区汉族组病人,差异有统计学意义(t=10.90,χ2=5.26,P<0.05)。维族组病人室间隔厚度高于汉族组病人,差异有统计学意义(t=2.52,P<0.05);新疆地区汉族组病人室间隔厚度大于上海地区汉族组病人,差异有统计学意义(t=3.31,P<0.05)。
结论 维族组女性围绝经期高血压病人中医证型以肝阳上亢最为常见,汉族组病人以肝肾阴虚最为常见。维族组病人血压较汉族组病人高,新疆地区汉族组病人血压较上海地区汉族组病人高,各组均以肝阳上亢证病人血压最高。维族组病人颈动脉IMT、颈动脉斑块检出率、室间隔厚度高于汉族组病人;新疆地区汉族组病人颈动脉IMT、颈动脉斑块检出率、室间隔厚度高于上海地区汉族组病人。
Abstract:
Objective  To investigate the distribution of traditional Chinese medicine (TCM) syndrome types in patients with perimenopausal hypertension from different nationalities and regions, and the association with target organ injury.
Methods Three hundred women with perimenopausal hypertension from different nationalities and regions were enrolled, and their general information, TCM symptoms, and target organ injury information were collected. TCM syndrome types, 24 h ambulatory blood pressure, carotid intima-media thickness (IMT), detection rate of carotid plaque, and interventricular septal thickness were compared between the women with perimenopausal hypertension of Uygur and Han nationalities and between the Han patients from Xinjiang and Shanghai.
Results  In the Uygur group, the TCM syndrome types in patients with perimenopausal hypertension, listed from more common to less common, were as follows: upper hyperactivity of liver Yang, phlegm-dampness stagnation, liver-kidney Yin deficiency, deficiency of both Qi and Yin. In the Han group, the TCM syndrome types, listed from more common to less common, were as follows: liver-kidney Yin deficiency, upper hyperactivity of liver Yang, deficiency of both Qi and Yin, and phlegm-dampness stagnation. There was a significant difference in the distribution of TCM syndrome types between the two groups (χ2=12.61,P<0.05). In the Han patients from Xinjiang, the TCM syndrome types, listed from more common to less common, were as follows: upper hyperactivity of liver Yang, liver-kidney Yin deficiency, deficiency of both Qi and Yin, and phlegm-dampness stagnation. In the Han patients from Shanghai, the TCM syndrome types, listed from more common to less common, were as follows: liver-kidney Yin deficiency, upper hyperactivity of liver Yang, deficiency of both Qi and Yin, and phlegm-dampness stagnation. There was no significant difference in the distribution of TCM syndrome types between the two groups (P>0.05). The patients in Uygur group had significantly higher 24 h systolic pressure and 24 h mean arterial pressure than those in Han group (t=2.85,3.46;P<0.05). The Han patients from Xinjiang had higher 24 h systolic pressure, 24 h diastolic pressure, and 24 h mean arterial pressure than those from Shanghai, but there was no significant difference between them (P>0.05). The patients with the syndrome of upper hyperactivity of liver Yang had the highest blood pressure in each group. The carotid IMT and detection rate of carotid plaque in the Uygur group were significantly higher than those in Han group (t=4.76,χ2=7.35,P<0.05). Furthermore, the above two indices in Han patients from Xinjiang were also significantly higher than those in Han patients from Shanghai (t=10.90,χ2=5.26,P<0.05). The interventricular septal thickness in the Uygur group was significantly higher than that in the Han group (t=2.52,P<0.05), and this index in Han patients from Xinjiang was also significantly higher than that in Han patients from Shanghai (t=3.31,P<0.05).
Conclusion  Upper hyperactivity of liver Yang is the most commonly seen TCM syndrome type in patients with perimenopausal hypertension of Uygur nationality, and liver-kidney Yin deficiency is the most commonly seen one in patients of Han nationality. The blood pressure is higher in Uygur patients than in Han patients, and is higher in Han patients from Xinjiang than in Han patients from Shanghai. The patients with the syndrome of upper hyperactivity of liver Yang have the highest blood pressure in each group. The Uygur patients have higher IMT, detection rate of carotid plaque, and interventricular septal thickness compared with the Han patients, and the Han patients from Xinjiang also have higher values of the three indices than the Han patients from Shanghai.
更新日期/Last Update: 2017-08-12