[1]殷晴,李群,秦晓红,等.我国癌症病人弓形虫感染情况Meta分析[J].齐鲁医学杂志,2017,32(06):681-684,687.[doi:10.13362/j.qlyx.201706014]
 YIN Qing,LI QUN,QIN Xiaohong,et al.SEROPREVALENCE OF TOXOPLASMA GONDII INFECTION IN CHINESE CANCER PATIENTS: A META-ANALYSIS[J].Medical Journal of Qilu,2017,32(06):681-684,687.[doi:10.13362/j.qlyx.201706014]
点击复制

我国癌症病人弓形虫感染情况Meta分析()
分享到:

《齐鲁医学杂志》[ISSN:1008-0341/CN:37-1280/R]

卷:
第32卷
期数:
2017年06期
页码:
681-684,687
栏目:
出版日期:
2018-03-20

文章信息/Info

Title:
SEROPREVALENCE OF TOXOPLASMA GONDII INFECTION IN CHINESE CANCER PATIENTS: A META-ANALYSIS
文章编号:
1008-0341(2017)06-0681-05
作者:
殷晴李群秦晓红张晓杰
吉林大学第一医院甲状腺外科,吉林 长春 130021
Author(s):
YIN Qing LI QUN QIN Xiaohong ZHANG Xiaojie
Thyroid Surgery of the First Hospital of Jilin University, Changchun 130021, China
关键词:
肿瘤弓形虫Meta分析
Keywords:
neoplasms Toxoplasma gondii Meta analysis
分类号:
R382.5
DOI:
10.13362/j.qlyx.201706014
文献标志码:
A
摘要:
目的 探讨我国癌症病人弓形虫感染情况及感染风险。
方法 检索2017年3月以前公开发表的关于我国癌症病人弓形虫感染风险的病例-对照研究,按照纳入与排除标准筛选文献、提取相关资料,进行Meta分析。
结果 最终纳入文献23篇,纳入癌症病人6 196例,对照人群7 852例。Meta分析结果显示,癌症病人弓形虫血清学阳性率为18.1%(95%CI=14.2~22.1),远高于对照人群的5.8%(95%CI=4.3~7.2);癌症组弓形虫感染风险是对照组的3.19倍(OR=3.19,95%CI=2.63~3.87)。
结论 癌症病人弓形虫血清学阳性率远高于正常人群,临床上治疗癌症病人时,应留意弓形虫继发感染,给予足够重视。
Abstract:
Objective  To investigate the seroprevalence and risk of Toxoplasma gondii infection in Chinese cancer patients.
Methods  We searched for the case-control studies on the risk of Toxoplasma gondii infection in Chinese cancer patients published up to March 2017. A Meta-analysis was performed after literature screening according to the inclusion and exclusion criteria as well as data extraction.
Results  A total of 23 case-control studies involving 6 196 cancer patients and 7 852 controls were included in the meta-analysis. The meta-analysis indicated that the pooled seroprevalence of Toxoplasma gondii infection in cancer patients was 18.1% (95% confidence interval (CI)=14.2-22.1), which was significantly higher than that in the control group (5.8%, 95% CI=4.3-7.2). The risk of Toxoplasma gondii infection in cancer patients was 3.19 times that in the control group (odds ratio=3.19, 95% CI=2.63-3.87).
Conclusion  Cancer patients have a significantly higher seroprevalence of Toxoplasma gondii infection than the normal population. Therefore, much attention should be paid to prevent secondary Toxoplasma gondii infection in treating cancer patients.
更新日期/Last Update: 2018-03-24