[1]孙楠,李红,高山,等.对乙酰氨基酚并舒芬太尼对新生儿开腹术后镇痛效果[J].齐鲁医学杂志,2017,32(06):722-724.[doi:10.13362/j.qlyx.201706026]
 SUN Nan,LI Hong,GAO Shan,et al.ANALGESIC EFFECT OF PARACETAMOL COMBINED WITH SUFENTANIL ON NEONATES AFTER LAPAROTOMY[J].Medical Journal of Qilu,2017,32(06):722-724.[doi:10.13362/j.qlyx.201706026]
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对乙酰氨基酚并舒芬太尼对新生儿开腹术后镇痛效果()
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《齐鲁医学杂志》[ISSN:1008-0341/CN:37-1280/R]

卷:
第32卷
期数:
2017年06期
页码:
722-724
栏目:
出版日期:
2018-03-20

文章信息/Info

Title:
ANALGESIC EFFECT OF PARACETAMOL COMBINED WITH SUFENTANIL ON NEONATES AFTER LAPAROTOMY
文章编号:
1008-0341(2017)06-0722-03
作者:
孙楠李红高山周建超
郑州大学第三附属医院药学部,河南 郑州 450052
Author(s):
SUN Nan LI Hong GAO Shan ZHOU Jianchao
Department of Pharmacy, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
关键词:
舒芬太尼醋氨酚婴儿新生镇痛
Keywords:
sufentanil acetaminophen infant newborn analgesia
分类号:
R614
DOI:
10.13362/j.qlyx.201706026
文献标志码:
A
摘要:
目的 评价对乙酰氨基酚联合舒芬太尼用于新生儿开腹术后镇痛的有效性及安全性。
方法 开腹术后新生儿60例,随机分为两组,A组静脉输入枸橼酸舒芬太尼注射液0.05 μg/(kg?h);B组静脉输入枸橼酸舒芬太尼注射液0.03 μg/(kg?h),联合肛门塞入对乙酰氨基酚栓20 mg/kg(每6 h用1次)。观察术后1、6、12、24 h两组病儿镇痛效果及不良反应。
结果 两组镇痛效果相当,不良反应发生率B组低于A组,差异有统计学意义(χ2=4.043,P<0.05)。
结论 对乙酰氨基酚联合舒芬太尼用于新生儿开腹术后镇痛效果良好,并且可以减少舒芬太尼用量及不良反应。
Abstract:
Objective  To investigate the efficacy and safety of paracetamol combined with sufentanil in analgesia for neonates after laparotomy.
Methods  A total of 60 neonates after laparotomy were randomly divided into groups A and B. The neonates in group A were given intravenous infusion of sufentanil citrate injection at a dose of 0.05 μg/(kg?h), and those in group B were given intravenous infusion of sufentanil citrate injection at a dose of 0.03 μg/(kg?h) combined with paracetamol suppositories 20 mg/kg once every 6 hours. The analgesic effect and adverse reactions were observed at 1,6,12, and 24 h after surgery.
Results The two groups had a comparable analgesic effect, and group B had a significantly lower incidence rate of adverse reactions than group A (χ2=4.043,P<0.05).
Conclusion  Paracetamol combined with sufentanil has a good analgesic effect in neonates after laparotomy and can reduce the dose of sufentanil and adverse reactions.
更新日期/Last Update: 2018-03-24